Caries Detector is absorbed into a typical plaque matrix and aids full debridement  prior to bonding, as the photos above of an Inlay-Flange bridge treatment sequence indicate. Caries Detector solution is applied, and once rinsed, any remnants can be debrided with a rotary brush, rotary cup,unfluoridated pumice, hand scaler, micro-abrader (sandblaster) with bicarbonate or aluminum oxide, interproximal strips, unwaxed dental floss, ultrasonic scaler,or any other imaginable device. These remanants are often very tenacious, so repeat caries detector following cleansing to verify complete debridement.

Where is plaque and debris removal  essential in the restorative sequence? Yes.In virtually every restorative procedure. But specifically, see

Removing plaque enhances marginal integrity of restorations and reduces the tendency of tissues to bleed unexpectedly during treatment, because areas of heavy plaque identified preoperatively are managed better during treatment. While carbide burs and Sandblasting remove plaque on the restorative substrate, caries detector is essential to remove plaque in adjacent areas.